产品货号：
Z25843
中文名称：
SDHD抗体
英文名称：
Anti-SDHD Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SDHD Antibody |
| 指标别名 | TRAP1,TRAP-1,SDH4,CII-4,CybS |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,ICC,IF |
| 基因名称 | SDHD |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | SDHD antibody was raised against a 15 amino acid synthetic peptide near the center of human SDHD.The immunogen is located within amino acids 30 - 80 of SDHD. |
| 计算分子量 | 17kDa |
| 成分 | SDHD Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | SDHD Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The mitochondrial succinate dehydrogenase complex subunit D (SDHD) is one of four proteins that make up the tricarboxylic cycle enzyme succinate dehydrogenase (SCH).Studies have shown that mutations in SDHD often leads to hereditary paragangliomas,usually benign tumors of the autonomic nervous system,suggesting that SDHD also plays a role as a tumor-suppressor gene.In one family with a nonsense mutation (R22X) in the SDHD gene,a loss of heterozygosity was found in the paragangliomas,and within these tumors the enzymatic activity of Complex II in the mitochondrial respiratory chain was completely abolished.Furthermore,high levels of angiogenic factors EPAS1 and VEGF was observed,which may stimulate tumor growth. |
| Uniprot ID | O14521 |
| 基因名全称 | Succinate dehydrogenase complex,subunit D,integral membrane protein |
| 蛋白名全称 | Succinate dehydrogenase complex,subunit D,integral membrane protein |
| 推荐稀释比 | SDHD antibody can be used for detection of SDHD by Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunocytochemistry starting at 2.5μg/mL.For immunofluorescence start at 2.5μg/mL.Antibody validated:Western Blot in mouse samples;Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples.All other applications and species not yet tested. |
相关搜索：SDHD抗体，SDHD多抗，Anti-SDHD Antibody